Targeting Toll-like receptors against cancer
نویسندگان
چکیده
منابع مشابه
The Role of Toll-Like Receptors in Breast Cancer
Breast cancer is highly prevalent worldwide. Treatment of this disease is a major global public health problem; therefore, numerous studies have explored new molecular profile helping for breast cancer therapy. Different risk factors are attributed to breast cancer; however, chronic inflammation and immune regulation are highly essential. Various molecules impact this context, including toll-li...
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Esophageal squamous cell carcinoma and esophageal adenocarcinoma are cancers of high mortality. EAC develops through Barrett's esophagus (BE) and columnar dysplasia, preceded by gastro-esophageal reflux disease. The risk of esophageal squamous cell carcinoma is increased by smoking and alcohol consumption. New treatment options for esophageal cancer are desperately needed. Toll-like receptors (...
متن کاملToll-Like Receptors and Prostate Cancer
Prostate cancer is the second leading cause of cancer-related death in men after lung cancer. Immune responses clearly play a critical role in the tumorigenesis and in the efficacy of radiation therapy and chemotherapy in prostate cancer; however, the underlying molecular mechanisms are still poorly understood. Toll-like receptors (TLRs) are a well-known family of pattern recognition receptors ...
متن کاملToll-Like Receptors and Skin Cancer
The skin, the largest organ in the body, provides the first line of defense against the environment both as a physical barrier and as a key immunological component. Toll-like receptors (TLRs) serve as signaling molecules that recognize pathogenassociated molecular patterns (PAMPs) as well as damage-associated molecular patterns (DAMPs), and are expressed by various skin cells including keratino...
متن کاملToll-like receptors and breast cancer
Toll-like receptors (TLRs) are key receptors in innate immunity and inflammation and are expressed not only in innate immune cells but also in different cancer cells. Increasing evidences demonstrate that TLRs play an important role in the initiation and progression of cancer and metabolism. Currently we have limited therapeutic options to treat patients with advanced non-resectable, recurrent ...
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ژورنال
عنوان ژورنال: Journal of Cancer Metastasis and Treatment
سال: 2016
ISSN: 2454-2857,2394-4722
DOI: 10.20517/2394-4722.2016.62